DMPK-BA Research Associate

The Drug Metabolism and Pharmacokinetics (DMPK) Department at Genentech is dedicated to enabling the discovery, development and commercialization of safe and effective medicines by elucidating the mechanisms of absorption, distribution, metabolism, and excretion of small molecule drug candidates. We accomplish our goals through the application of state-of-the-art  technologies for bioanalysis, drug metabolism, drug transport and  pharmacokinetics. The DMPK department works in close partnership with disciplines such as medicinal chemistry, in vivo pharmacology, toxicology, pharmaceutical sciences, clinical pharmacology and regulatory to optimize lead compounds, select clinical candidates, conduct preclinical studies, support clinical development and contribute to IND and NDA filings. 

Job Description 

The responsibilities of a DMPK-BA Research Associate include: Perform bioanalytical assays to support in-house pharmacokinetic (PK) and toxicokinetic (TK) studies; adapt new technology platforms and novel tools for DMPK challenges; maintain current knowledge of latest bioanalytical methods and technologies; enhance bioanalytical capability by implementing automation and improving study/process workflow for increased efficiency and throughput.

Qualified candidate for the DMPK-BA Research Associate position should possess a B.S. with 2–5 years of relevant industry/research experience focused on liquid chromatography-mass spectrometry (LC-MS) analysis of small molecules and peptides, or has a M.S. degree in analytical chemistry, pharmaceutical science, or related discipline. Hands-on experience with biological sample preparation and LC-MS analysis is required; experience with Sciex triple quadruple is a plus. The candidate needs to possess a demonstrated ability to work  independently in a fast-paced environment, as well as in a team setting. The candidate should have excellent organizational and communication skills.